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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
27.27
Human Site:
Y318
Identified Species:
46.15
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
Y318
Y
R
M
R
Q
L
G
Y
P
P
G
W
L
K
E
Chimpanzee
Pan troglodytes
XP_509445
540
59236
K157
G
Y
P
P
G
W
L
K
E
A
E
L
E
N
S
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
Y318
Y
R
M
R
Q
L
G
Y
P
P
G
W
L
K
E
Dog
Lupus familis
XP_534658
709
78944
Y318
Y
R
M
R
Q
L
G
Y
P
P
G
W
L
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
Y321
Y
R
M
R
Q
L
G
Y
P
P
G
W
L
K
E
Rat
Rattus norvegicus
NP_001099399
476
51796
I93
D
K
S
L
P
P
F
I
Y
R
M
R
Q
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
Y315
Y
R
M
R
Q
L
G
Y
P
P
G
W
L
K
E
Chicken
Gallus gallus
Q5F3D1
613
68449
S230
K
E
A
E
M
E
H
S
G
L
A
L
Y
D
G
Frog
Xenopus laevis
Q6DD45
743
82926
Y303
Y
R
M
R
E
L
G
Y
P
P
G
W
L
K
E
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
Y302
Y
R
M
R
E
L
G
Y
P
P
G
W
L
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
A170
E
E
R
K
K
L
K
A
E
A
V
N
K
C
F
Honey Bee
Apis mellifera
XP_001122586
556
62911
N173
F
N
C
L
E
N
H
N
L
R
D
C
P
E
P
Nematode Worm
Caenorhab. elegans
P34656
453
51815
E70
K
L
N
A
E
D
V
E
K
S
G
E
D
I
G
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
A243
I
S
D
A
L
R
Q
A
M
G
L
S
S
N
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
100
0
93.3
93.3
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
0
100
100
N.A.
100
6.6
N.A.
100
0
100
100
N.A.
20
20
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
0
0
15
0
15
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
8
0
8
0
0
8
0
0
0
0
8
0
8
8
0
% D
% Glu:
8
15
0
8
29
8
0
8
15
0
8
8
8
8
50
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
8
0
50
0
8
8
58
0
0
0
22
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
15
8
0
8
8
0
8
8
8
0
0
0
8
50
0
% K
% Leu:
0
8
0
15
8
58
8
0
8
8
8
15
50
8
0
% L
% Met:
0
0
50
0
8
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
8
8
0
0
8
0
8
0
0
0
8
0
15
0
% N
% Pro:
0
0
8
8
8
8
0
0
50
50
0
0
8
0
8
% P
% Gln:
0
0
0
0
36
0
8
0
0
0
0
0
8
0
8
% Q
% Arg:
0
50
8
50
0
8
0
0
0
15
0
8
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
8
0
8
0
8
8
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
50
0
0
0
% W
% Tyr:
50
8
0
0
0
0
0
50
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _